2. Splenic cord is mainly composed of reticular fibers & cells (which is the framework of lymphoid tissues), macrophages, Blood (i.e. RBC & other leukocytes).
Red Pulp is like a open space cavity filled with blood. In Splenic cord macrophages are present which phagocytose the damaged, expired, RBC(erythrocyte). So, the chief & important function of Spleen is to filter out the blood & scavenger of RBC(erythrocytes).
Main Function of Spleen:
1. Filter blood by removing worn-out RBC & micro agents - (which occur around Red Pulp). 2. Produce new lymphocytes which is later transported through blood-stream to target site - (Production occur around White Pulp).
If any antigen/pathogens are present then, White Pulp begins to produce more & more lymphocytes as a defense mechanism.
Microcirculation in Spleen:
1. Open/Slow Circulation:
Central arteriole → Penicillar artery → Open space around red pulp→ Venous sinusoid → Trabecular Vein → Splenic vein